MICROPLAITE | a microfluidic platform for tissue reconstruction

A cross-Border and innovative platform for faster tissue reconstruction 

The MICROPLAITE project aims to accelerate the development of medical devices for tissue reconstruction. This unique microfluidic platform will replicate the microenvironment of natural tissues, reducing the need for in vivo animal testing. An ambitious initiative that combines technological innovation with social impact, funded by the Interreg France-Wallonia-Flanders program. 

Context 

The rise of chronic diseases, cancer, and trauma increases the need for therapeutic solutions in tissue reconstruction. In Europe, the market for bone graft materials has grown by over 6% in the past decade. The demand for tissue reconstruction therapies continues to rise equally. 

The MICROPLAITE project was launched to improve access to tissue reconstruction treatments for patients suffering from soft tissue injuries, particularly those caused by cancer, diabetes, burns, or accidents—which are common in the Interreg France-Wallonia-Flanders region. 

• In Wallonia and Flanders, the incidence of soft tissue and bone cancers is above the European average. The Hauts-de-France region has the highest rate in France. 
• According to the Burns Foundation, nearly 120,000 people in Belgium suffer burns annually. More than half of them are children under 5 years old. The Hauts-de-France region has the highest rate in mainland France. 
• Diabetes affects 6.2% of the population in Hauts-de-France and 6.6% of the Belgian population. Soft tissue complications, particularly diabetic foot, are common. In 21% of cases, this leads to amputation. 

Additionally, existing therapies are often expensive and complex, making them less accessible. The project partners aim to overcome these challenges by introducing innovative, targeted, and accessible solutions for cell regeneration. 

Objectives and results 

Through cross-border collaboration with Interreg, the MICROPLAITE project aims to develop advanced medical technologies that address the growing demand for tissue regeneration solutions.

The goal of MICROPLAITE is to miniaturize an innovative device for cell growth and analysis, which is expected to provide significant advantages in terms of precision and flexibility. The system is designed for broader application than current technologies, marking a major technological breakthrough.

The project also seeks to validate key properties of medical devices, including: 

•  Antimicrobial effectiveness
• Biosafety
• Reduction of animal testing through more realistic simulations 

The aim is to democratize tissue reconstruction therapies, making these technologies more accessible to a wider audience. 

Approach 

The project brings together interdisciplinary expertise across borders, including: 

• Micro-/meso-fluidic engineering expertise for the development of highly precise devices. 
• Advanced knowledge of biomaterials and cell sciences to ensure the effectiveness and safety of the proposed solutions. 

Collaboration between partners will leverage complementary infrastructures and expertise to achieve the project’s ambitious goals. 

Target audience 

The MICROPLAITE project primarily focuses on: 

• Patients with soft tissue injuries, particularly those linked to cancer, diabetes, burns, or accidents. 
• Healthcare professionals seeking access to advanced therapeutic solutions.  
• Researchers and industry professionals specializing in the development of biomaterials and medical devices. 

Funding 

The MICROPLAITE project has received €2.8 million in funding under the Interreg France-Wallonia-Flanders program. This support highlights the strategic importance of the initiative for the region and innovation in healthcare.